BDBM238342 US9394275, I-57

SMILES C[C@@H](NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12)c1cccc(CCNC(=O)c2ccc(cc2)N(C)C(=O)CCN2CCC(CC2)OC(=O)Nc2ccccc2-c2ccccc2)c1

InChI Key InChIKey=KOHQSQYVBTZTTO-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238342   

TargetBeta-2 adrenergic receptor(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM238342(US9394275, I-57)
Affinity DataEC50:  1nMT: 2°CAssay Description:cAMP assays were performed in a radioimmunoassay format using the Flashplate Adenylyl Cyclase Activation Assay System with [125I]-cAMP (NEN SMP004, P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetMuscarinic acetylcholine receptor M3(Human)
Theravance Respiratory

US Patent
LigandPNGBDBM238342(US9394275, I-57)
Affinity DataKi:  0.100nM ΔG°:  -14.2kcal/moleT: 2°CAssay Description:Displacement assays for determination of Ki values of test compounds were performed with [3H]-NMS at 1 nM and eleven different test compound concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent