BDBM238318 US9394273, 7

SMILES OC(Cc1cccc(Cl)c1)\C=C\[C@H]1CCC(=O)[C@@H]1CCc1ccc(cc1)C(O)=O

InChI Key InChIKey=YQAHEMJLXLEJPE-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 238318   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataEC50:  123nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataEC50:  2nMpH: 7.4 T: 2°CAssay Description:A 384-well drug plate was prepared to contain test compounds, PGE2 and cAMP in 16 serial dilutions in triplicate, using a Biomek station. HEK-EBNA ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetThromboxane A2 receptor(Human)
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataEC50:  4.83E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in Biocoati Poly-D-lysine-coated black-wall, clear-botto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataKi:  2nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP2 subtype(Human)
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataKi:  2.76E+3nMAssay Description: The cell homogenate was centrifuged at 19000 r.p.m. for 20 min at 4° C. using a Beckman Ti-60 rotor. The resultant pellet was resuspended in TME buf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/18/2017
Entry Details
Go to US Patent