BDBM238304 4-benzoyl-1-(3-(2-(1,3-dioxo-1,3-diphenylpropan-2-ylidene)hydrazinyl)phenyl)-5-phenyl-N-(4-sulfamoylphenyl)-1H-pyrazole-3-carboxamide (6)

SMILES [#7]S(=O)(=O)c1ccc(-[#7]-[#6](=O)-c2nn(c(c2-[#6](=O)-c2ccccc2)-c2ccccc2)-c2cccc(-[#7]\[#7]=[#6](\[#6](=O)-c3ccccc3)-[#6](=O)-c3ccccc3)c2)cc1

InChI Key InChIKey=HXSCJFMQNHMDCJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238304   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM238304(4-benzoyl-1-(3-(2-(1,3-dioxo-1,3-diphenylpropan-2-...)
Affinity DataKi:  1.95E+3nM ΔG°:  -7.79kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM238304(4-benzoyl-1-(3-(2-(1,3-dioxo-1,3-diphenylpropan-2-...)
Affinity DataKi:  4.10E+3nM ΔG°:  -7.34kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed