BDBM238302 4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-2-yl)diazenyl)phenyl)-5-phenyl-N-(4-sulfamoylphenyl)-1Hpyrazole-3-carboxamide (7)

SMILES CC(=O)C(=N/Nc1cccc(c1)-n1nc(C(=O)Nc2ccc(cc2)S(N)(=O)=O)c(C(=O)c2ccccc2)c1-c1ccccc1)\C(=O)c1ccccc1

InChI Key InChIKey=TXWUUZDBZACAGU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238302   

TargetCarbonic anhydrase 2(Human)
Dumlupinar University

LigandPNGBDBM238302(4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-...)
Affinity DataKi:  166nM ΔG°:  -9.24kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Dumlupinar University

LigandPNGBDBM238302(4-benzoyl-1-(3-((3-hydroxy-1-oxo-1-phenylbut-2-en-...)
Affinity DataKi:  521nM ΔG°:  -8.57kcal/molepH: 7.4 T: 2°CAssay Description:CA activity was assayed in inhibition studies by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed