BDBM238273 US9409887, I-4

SMILES COc1cc(NC(C)C)ccc1Nc1ncc(Cl)c(Nc2cccc(NC(=O)C=C)c2)n1

InChI Key InChIKey=IEZFFFOOLULQBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238273   

TargetEpidermal growth factor receptor [668-1210](Human)
Celgene Avilomics Research

US Patent
LigandPNGBDBM238273(US9409887, I-4)
Affinity DataIC50: 65nMpH: 7.5Assay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [668-1210,T790M,L858R](Human)
Celgene Avilomics Research

US Patent
LigandPNGBDBM238273(US9409887, I-4)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Briefly, 10× stocks of EGFR-WT (PV3872) from Invitrogen and EGFR-T790M/L858R (40350) from BPS Bioscience, San Diego, Calif., 1.13×ATP (AS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent