BDBM237533 US9393232, 4.6a::US9393232, 4.6b

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N3CCC[C@@H](N)C3)(c3ccsc3)c2c1

InChI Key InChIKey=REVXYXMYDPWVSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237533   

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237533(US9393232, 4.6b | US9393232, 4.6a)
Affinity DataIC50: 30nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237533(US9393232, 4.6b | US9393232, 4.6a)
Affinity DataIC50: 24nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent