BDBM23753 3-{4-[(4-octadecylpiperazin-1-yl)methyl]phenyl}-4,5-dihydro-1,2,4-oxadiazol-5-one::PMS 1062 piperazine deriv., 23c

SMILES CCCCCCCCCCCCCCCCCCN1CCN(Cc2ccc(cc2)-c2nc(=O)o[nH]2)CC1

InChI Key InChIKey=ORLPULOZISVXAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23753   

TargetPhospholipase A2, membrane associated(Human)
Universite Paris 7-Denis Diderot

LigandPNGBDBM23753(3-{4-[(4-octadecylpiperazin-1-yl)methyl]phenyl}-4,...)
Affinity DataIC50: 5.08E+3nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Universite Paris 7-Denis Diderot

LigandPNGBDBM23753(3-{4-[(4-octadecylpiperazin-1-yl)methyl]phenyl}-4,...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
Universite Paris 7-Denis Diderot

LigandPNGBDBM23753(3-{4-[(4-octadecylpiperazin-1-yl)methyl]phenyl}-4,...)
Affinity DataIC50: 5.08E+3nMAssay Description:Inhibition of human recombinant group 2A phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Universite Paris 7-Denis Diderot

LigandPNGBDBM23753(3-{4-[(4-octadecylpiperazin-1-yl)methyl]phenyl}-4,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of porcine group 1B phospholipase A2 by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed