BDBM237482 US9393232, 2.59::US9393232, 2.59a::US9393232, 2.59b

SMILES Cc1noc(C)c1-c1ccc2NC(=O)C(N)(c2c1)c1ccc(F)cc1

InChI Key InChIKey=NRJFQLRIZKGSPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 237482   

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237482(US9393232, 2.59a | US9393232, 2.59b | US9393232, 2...)
Affinity DataIC50: 97nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237482(US9393232, 2.59a | US9393232, 2.59b | US9393232, 2...)
Affinity DataIC50: 4.10E+3nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBromodomain-containing protein 4 [1-477](Human)
Beigene

US Patent
LigandPNGBDBM237482(US9393232, 2.59a | US9393232, 2.59b | US9393232, 2...)
Affinity DataIC50: 36nMpH: 7.5Assay Description:The assay was carried out in binding mixtures of the bromodomain protein, 0-10 μM compounds and tetra-acetylated histone peptide (SGRGAC.KGGAC.K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent