BDBM237339 CA inhibitor, 12

SMILES Cc1ccc(cc1)S(=O)(=O)N(c1ccccc1)c1ccccc1

InChI Key InChIKey=VLYSRNWCIRFSSM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237339   

TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237339(CA inhibitor, 12)
Affinity DataKi:  377nM ΔG°:  -8.76kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237339(CA inhibitor, 12)
Affinity DataKi:  459nM ΔG°:  -8.64kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed