BDBM237303 N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9)

SMILES CCc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

InChI Key InChIKey=GZDITLVHGUKNBP-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237303   

TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50: 4.48E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50: 977nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataIC50: 2.65E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataKi:  533nM ΔG°:  -8.55kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ataturk University

LigandPNGBDBM237303(N-(4-ethylphenyl)-4-methylbenzenesulfonamide (9))
Affinity DataKi:  753nM ΔG°:  -8.35kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed