BDBM237286 CA inhibitor, 5d

SMILES Cc1ccc(o1)-c1c2CCCc2nc(N)c1C#N

InChI Key InChIKey=WHNKUKRKJZVMIM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237286   

TargetCarbonic anhydrase 1(Human)
Gazi University

LigandPNGBDBM237286(CA inhibitor, 5d)
Affinity DataKi:  2.38E+4nM IC50: 3.30E+4nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Gazi University

LigandPNGBDBM237286(CA inhibitor, 5d)
Affinity DataKi:  4.10E+4nM IC50: 5.60E+4nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a period of 3 min ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed