BDBM237256 (E)-3-(3,4-Dihydroxyphenyl)-N-(4-(3,4-Difluorophenylsulfamoyl)phenyl)acrylamide (11b)

SMILES Oc1ccc(\C=C\C(=O)Nc2ccc(cc2)S(=O)(=O)Nc2ccc(F)c(F)c2)cc1O

InChI Key InChIKey=QWXNTUQKFPPQHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 237256   

TargetGag-Pol polyprotein(HIV-1)
Shandong University

LigandPNGBDBM237256((E)-3-(3,4-Dihydroxyphenyl)-N-(4-(3,4-Difluorophen...)
Affinity DataIC50: 1.10E+4nMAssay Description:Cleavage of a dinucleotide from each 3'-end of viral cDNA. All biological assays were performed essentially as previously described [Dayam et al....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetGag-Pol polyprotein(HIV-1)
Shandong University

LigandPNGBDBM237256((E)-3-(3,4-Dihydroxyphenyl)-N-(4-(3,4-Difluorophen...)
Affinity DataIC50: 6.00E+3nMAssay Description:Insertion of two newly processed 3'-viral DNA ends into the host-cell chromosome. All biological assays were performed essentially as previously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed