BDBM237158 US9394307, 4-chloro-N-(2-{5-methoxy-1H,3aH,7aH-pyrrolo[2,3-b]pyridine-4-carbonyl}-5-methylpyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonamide

SMILES COC1=C(C2C=CNC2N=C1)C(=O)c1ncc(C)cc1NS(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=NHDSZRPQPRUVFE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237158   

TargetCytochrome P450 3A4(Human)
Chemocentryx

US Patent
LigandPNGBDBM237158(US9394307, 4-chloro-N-(2-{5-methoxy-1H,3aH,7aH-pyr...)
Affinity DataIC50: 3.00E+3nMT: 2°CAssay Description:The test compounds were incubated with pooled human liver microsomes at 37° C. in the presence of NADPH and appropriate concentrations of substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details
Go to US Patent