BDBM23586 (3-Phenoxybenzoylamino)benzoic acid deriv., 31::2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzoic acid

SMILES OC(=O)c1c(O)cccc1NC(=O)c1ccc(Br)c(Oc2ccccc2)c1

InChI Key InChIKey=DZBMWOJXZNLVRL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 23586   

Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 62nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 34nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 1.23E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandPNGBDBM23586(2-[(4-bromo-3-phenoxybenzene)amido]-6-hydroxybenzo...)
Affinity DataIC50: 2.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed