BDBM23584 (3-Phenoxybenzoylamino)benzoic acid deriv., 24c::2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid

SMILES OC(=O)c1ccccc1NC(=O)c1ccc(c(Oc2ccccc2)c1)-c1ccccc1

InChI Key InChIKey=RYMAXBJFTSZAJG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23584   

Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 56nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes serotype M3)
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae (strain ATCC 51907 / DSM 11...)
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 1.00E+5nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis (strain ATCC 700802 / V583))
Quorex Pharmaceuticals

LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 56.0nMAssay Description:Inhibition of Enterococcus faecalis FabH by FabD/FabH coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target3-oxoacyl-ACP synthase(Pseudomonas aeruginosa)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM23584(2-[(3-phenoxy-4-phenylbenzene)amido]benzoic acid |...)
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at Pseudomonas aeruginosa PqsDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed