BDBM235774 US9359372, DC037024

SMILES COc1cc2CC3N(CCc4cc(O)c(O)cc34)Cc2cc1OC

InChI Key InChIKey=BTUIZHMEGKWEMO-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235774   

TargetD(2) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM235774(US9359372, DC037024)
Affinity DataEC50:  591nMT: 2°CAssay Description:Each medicament was dissolved in serum-free F12 culture medium containing 100 μM of IBMX. CHO cells which can stably express D2 receptor were pre-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetD(1A) dopamine receptor(Human)
Shanghai Institute of Material Medica, Chinese Academy of Sciences

US Patent
LigandPNGBDBM235774(US9359372, DC037024)
Affinity DataKi:  741nM ΔG°:  -8.50kcal/mole IC50: 1.50E+3nMT: 2°CAssay Description:Different concentrations (10^−5 M-10^−11 M) of the compound of the invention and corresponding isotope receptor ligand as well as recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent