BDBM235728 US10117875, Example 71::US9359361, 71

SMILES FC(F)(F)c1nc2c(NCCN3CCOCC3)nc(nc2n(CCN2CCOCC2)c1=O)-c1ccccc1

InChI Key InChIKey=QXCKCDQXRMWEJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235728   

TargetToll-like receptor 9(Human)
Janus Biotherapeutics

US Patent
LigandPNGBDBM235728(US9359361, 71 | US10117875, Example 71)
Affinity DataIC50: 3.82E+3nMT: 2°CAssay Description:Day 1: A cell suspension of HEK-Blue™-hTLR9 cells at ~450,000 cells per ml in test medium which contained 5% (v/v) heat inactivated FBS was pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
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TargetToll-like receptor 9(Human)
Janus Biotherapeutics

US Patent
LigandPNGBDBM235728(US9359361, 71 | US10117875, Example 71)
Affinity DataIC50: 3.82E+3nMAssay Description:HEK-Blue-hTLR9 cells were obtained from InvivoGen Inc. and used to determine test compound antagonism of human TLR9 (hTLR9) driven responses. HEK-Blu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
Go to US Patent