BDBM23567 3-Carboxamide-coumarin deriv., 45::8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chromene-3-carboxamide

SMILES Cc1cccc(NC(=O)c2cc3cc(Cl)cc(Br)c3oc2=O)c1

InChI Key InChIKey=AOZYTCBDNDDZPR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23567   

TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23567(8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chrom...)
Affinity DataIC50: 1.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23567(8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23567(8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chrom...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23567(8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23567(8-bromo-6-chloro-N-(3-methylphenyl)-2-oxo-2H-chrom...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed