BDBM23563 3-Carboxylate-coumarin deriv., 3::CHEMBL13357::phenyl 6-(chloromethyl)-2-oxo-2H-chromene-3-carboxylate

SMILES ClCc1ccc2oc(=O)c(cc2c1)C(=O)Oc1ccccc1

InChI Key InChIKey=VLAVQNSKKDLVGI-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23563   

TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23563(CHEMBL13357 | phenyl 6-(chloromethyl)-2-oxo-2H-chr...)
Affinity DataIC50: 5.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23563(CHEMBL13357 | phenyl 6-(chloromethyl)-2-oxo-2H-chr...)
Affinity DataIC50: 7.00E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23563(CHEMBL13357 | phenyl 6-(chloromethyl)-2-oxo-2H-chr...)
Affinity DataIC50: 5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23563(CHEMBL13357 | phenyl 6-(chloromethyl)-2-oxo-2H-chr...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23563(CHEMBL13357 | phenyl 6-(chloromethyl)-2-oxo-2H-chr...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Université

Curated by ChEMBL
LigandPNGBDBM23563(CHEMBL13357 | phenyl 6-(chloromethyl)-2-oxo-2H-chr...)
Affinity DataKi:  340nMAssay Description:Compound was tested for the binding affinity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed