BDBM235521 US9359338, Exe. 131

SMILES CN1CCC(CC1)Nc1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)nc2)cc(c1)C(F)(F)F

InChI Key InChIKey=ZDUYBXCDPILNJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235521   

TargetVascular endothelial growth factor receptor 2 [790-1356](Human)
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235521(US9359338, Exe. 131)
Affinity DataIC50: 6.10nMT: 2°CAssay Description:[Experimental method]: Use Lance@Ultra Ulight™-TK assay kit from PerKinElmer to evaluate the inhibitory activity of compounds at KDR kinase. [I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
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TargetSerine/threonine-protein kinase B-raf(Human)
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235521(US9359338, Exe. 131)
Affinity DataIC50: 12.5nMT: 2°CAssay Description:[Experimental method]: Use ADP-GLO™ assay kit from Promega to evaluate the inhibitory activity of compounds at B-Raf. [Instrument]: PerKinElmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
Go to US Patent