BDBM23545 3-Carboxamide-coumarin deriv., 35::6-nitro-2-oxo-N-phenyl-2H-chromene-3-carboxamide

SMILES [O-][N+](=O)c1ccc2oc(=O)c(cc2c1)C(=O)Nc1ccccc1

InChI Key InChIKey=NDMMIVPXGAPYKM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23545   

TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23545(6-nitro-2-oxo-N-phenyl-2H-chromene-3-carboxamide |...)
Affinity DataIC50: 2.20E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23545(6-nitro-2-oxo-N-phenyl-2H-chromene-3-carboxamide |...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23545(6-nitro-2-oxo-N-phenyl-2H-chromene-3-carboxamide |...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23545(6-nitro-2-oxo-N-phenyl-2H-chromene-3-carboxamide |...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23545(6-nitro-2-oxo-N-phenyl-2H-chromene-3-carboxamide |...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed