BDBM235419 US9359338, Exe. 029

SMILES Fc1cc(Oc2ccnc(NC(=O)C3CC3)c2)ccc1NC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=HUJRSGGBAXUNTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235419   

TargetSerine/threonine-protein kinase B-raf(Human)
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235419(US9359338, Exe. 029)
Affinity DataIC50: 7.30nMT: 2°CAssay Description:[Experimental method]: Use ADP-GLO™ assay kit from Promega to evaluate the inhibitory activity of compounds at B-Raf. [Instrument]: PerKinElmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2 [790-1356](Human)
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235419(US9359338, Exe. 029)
Affinity DataIC50: 3.90nMT: 2°CAssay Description:[Experimental method]: Use Lance@Ultra Ulight™-TK assay kit from PerKinElmer to evaluate the inhibitory activity of compounds at KDR kinase. [I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
Go to US Patent