BDBM235397 US9359338, Exe. 007

SMILES FC(F)(F)c1cc(NC(=O)Nc2ccc(Oc3cc(NC(=O)C4CC4)ncn3)cc2)ccc1Cl

InChI Key InChIKey=VJXYXBNJVZLNDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235397   

TargetSerine/threonine-protein kinase B-raf(Human)
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235397(US9359338, Exe. 007)
Affinity DataIC50: 24.8nMT: 2°CAssay Description:[Experimental method]: Use ADP-GLO™ assay kit from Promega to evaluate the inhibitory activity of compounds at B-Raf. [Instrument]: PerKinElmer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
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TargetVascular endothelial growth factor receptor 2 [790-1356](Human)
Crown Bioscience Inc. (Taiwan)

US Patent
LigandPNGBDBM235397(US9359338, Exe. 007)
Affinity DataIC50: 5.70nMT: 2°CAssay Description:[Experimental method]: Use Lance@Ultra Ulight™-TK assay kit from PerKinElmer to evaluate the inhibitory activity of compounds at KDR kinase. [I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2017
Entry Details
Go to US Patent