BDBM23538 3-Carboxamide-coumarin deriv., 20::6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide

SMILES Cc1ccc2oc(=O)c(cc2c1)C(=O)Nc1ccccc1

InChI Key InChIKey=JUQDUATUBQVGDN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23538   

TargetCoagulation factor XII(Human)
University of Namur

LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataIC50: 2.30E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Namur

LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataIC50: 5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Namur

LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Namur

LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Namur

LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataIC50: 5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2008
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Porto

Curated by ChEMBL
LigandPNGBDBM23538(6-methyl-2-oxo-N-phenyl-2H-chromene-3-carboxamide ...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2019
Entry Details Article
PubMed