BDBM23532 2-{3-[1-(5-hydroxypyridin-2-yl)-1H-pyrazol-3-yl]propanamido}benzoic acid::Biaryl Anthranilide Analogue, 2n

SMILES OC(=O)c1ccccc1NC(=O)CCc1ccn(n1)-c1ccc(O)cn1

InChI Key InChIKey=PLXBCICQWMMKFY-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23532   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23532(2-{3-[1-(5-hydroxypyridin-2-yl)-1H-pyrazol-3-yl]pr...)
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]niacin from GRP109A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23532(2-{3-[1-(5-hydroxypyridin-2-yl)-1H-pyrazol-3-yl]pr...)
Affinity DataIC50: 58nM EC50:  1.30E+3nMpH: 7.4 T: 2°CAssay Description:Membranes were incubated in binding buffer with [5, 6-3H]-niacin in the presence of test compound. After 4 hours at room temperature, reactions were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2008
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM23532(2-{3-[1-(5-hydroxypyridin-2-yl)-1H-pyrazol-3-yl]pr...)
Affinity DataEC50:  1.30E+3nMAssay Description:Displacement of [3H]niacin from GRP109A receptor in presence of 4% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed