BDBM235160 US9359345, 6

SMILES Cc1cccc(CC(=O)N[C@@H]2CCCN(C2)c2nc(C(N)=O)c(Nc3ccccn3)s2)c1

InChI Key InChIKey=KUDOTDSVZMKXCG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 235160   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM235160(US9359345, 6)
Affinity DataIC50: 7.51E+3nMpH: 7.15 T: 2°CAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Forster/Fluorescence Re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent