BDBM234979 US9556168, 1F

SMILES CC(c1c(Cl)cccc1C(F)(F)F)n1nc(-c2ccc(cc2F)C(O)=O)c2c(F)cccc12

InChI Key InChIKey=DVHGXCCMQJBABK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234979   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM234979(US9556168, 1F)
Affinity DataIC50: 1.55E+3nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
US Patent