BDBM234978 US9556168, 1E

SMILES OC(=O)c1c(F)cc(cc1F)-c1nn(Cc2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12

InChI Key InChIKey=PTLLQRIDZAPKIB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234978   

TargetNuclear receptor ROR-gamma(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM234978(US9556168, 1E)
Affinity DataIC50: 219nMpH: 7.0Assay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
US Patent