BDBM234549 US9353089, 313

SMILES COc1ccc(cc1)C1(NC(=N)N(CC2CCN(CC2)C(=O)OC(C)(C)C)C1=O)c1ccc(OC)cc1

InChI Key InChIKey=FHVISDKTJAQQPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 234549   

TargetPlasmepsin II(Plasmodium falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234549(US9353089, 313)
Affinity DataIC50: 11nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
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TargetBeta-secretase 1(Human)
Saint Louis University

US Patent
LigandPNGBDBM234549(US9353089, 313)
Affinity DataIC50: 2.20E+3nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent