BDBM234501 US9353089, 128

SMILES COc1cccc(c1)C1(NC(=N)N(C2CCCCC2)C1=O)c1cccc(OC)c1

InChI Key InChIKey=CFOCZHLGHZFLCC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 234501   

TargetPlasmepsin II(Plasmodium falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 36nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
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TargetPlasmepsin IV [1-448](malaria parasite P. falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 41nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 2.89E+4nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent

TargetCathepsin D(Human)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 1.10E+3nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent

TargetCathepsin E(Human)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 1.86E+3nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent

TargetPlasmepsin II(Plasmodium falciparum)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 35.9nMpH: 4.5 T: 2°CAssay Description:Plasmepsin-2 (PM-2; Plm II) and Plasmepsin (PM-4; Plm IV) expression and purification was performed following the published protocols (Istvan E S and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent

TargetBeta-secretase 1(Human)
Saint Louis University

US Patent
LigandPNGBDBM234501(US9353089, 128)
Affinity DataIC50: 2.89E+4nMpH: 4.0 T: 2°CAssay Description:The recombinant human BACE1, Cathepsin D, and Cathepsin E enzymes were purchased from R&D Systems (catalog numbers are 931-AS, 1014AS and 1294AS, res...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details
Go to US Patent