BDBM233897 US9353090, 25::US9353090, 26

SMILES Cc1cccc(-c2cccc(n2)N2C[C@@H]3C[C@@]3(C2)C(O)=O)c1OCc1cc(C)c2CN(CCc2c1)C1CCOC1

InChI Key InChIKey=MEGGMDJNTHBGBC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 233897   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM233897(US9353090, 26 | US9353090, 25)
Affinity DataEC50:  16nMT: 2°CAssay Description:The sGC cellular activator assay is performed in the presence and absence of 50% human serum (HS) using Chinese hamster ovary cells that have been st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM233897(US9353090, 26 | US9353090, 25)
Affinity DataEC50:  9nMT: 2°CAssay Description:The sGC cellular activator assay is performed in the presence and absence of 50% human serum (HS) using Chinese hamster ovary cells that have been st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent