BDBM233718 US9353066, 3.16

SMILES COCCCOc1ccc(cc1C(O)=O)-c1cc(C)cc(Nc2nccc(n2)C(F)(F)F)c1

InChI Key InChIKey=UPBIXZNWUPTBFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233718   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233718(US9353066, 3.16)
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:A recombinant GST-hSYK fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-SYK (Carna Bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent