BDBM23322 3,3-dimethyl-1-[(2S)-2-{5-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]pentanoyl}pyrrolidin-1-yl]pentane-1,2-dione::N-Glyoxylprolyl ketone, 5e

SMILES CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)CCCCc1c(F)c(F)c(c(F)c1F)C(F)(F)F

InChI Key InChIKey=VAWIHHCJRBQOLP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23322   

TargetPeptidyl-prolyl cis-trans isomerase FKBP1A(Bovine)
Guilford Pharmaceuticals

LigandPNGBDBM23322(3,3-dimethyl-1-[(2S)-2-{5-[2,3,5,6-tetrafluoro-4-(...)
Affinity DataKi:  130nM ΔG°:  -8.60kcal/molepH: 8.0 T: 2°CAssay Description:PPIase(Rotamase) activity of FKBP12 was assayed using the peptide N-succinyl Ala-Leu-Pro-Phe p-nitroanilide as substrate. It is based on the observat...More data for this Ligand-Target Pair
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Date in BDB:
7/12/2008
Entry Details Article
PubMed