BDBM233190 1-Cyclopropyl-6-fluoro-7-4-[(5-nitro-2,6-dioxohexahydro-4-pyrimidinyl)carbonyl]piperazino-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (3l)

SMILES OC(=O)c1cn(C2CC2)c2cc(N3CCN(CC3)C(=O)C3NC(=O)NC(=O)C3[N+]([O-])=O)c(F)cc2c1=O

InChI Key InChIKey=MZFGLVCGWGGABZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 233190   

TargetIsocitrate lyase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Birla Institute of Technology

LigandPNGBDBM233190(1-Cyclopropyl-6-fluoro-7-4-[(5-nitro-2,6-dioxohexa...)
Affinity DataIC50: 1.21E+5nMT: 2°CAssay Description:Isocitrate lyase activity was determined at 37°C by measuringthe formation of glyoxylate phenylhydrazone at 324 nm [Bai et al., Drug Dev. Res., 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed