BDBM233105 N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N'-(2,4-difluorophenyl)urea (11f)

SMILES COc1cc2ncnc(Nc3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)c2cc1OC

InChI Key InChIKey=SIBBDCDYYYTSNN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 233105   

TargetEpidermal growth factor receptor(Human)
Universit�� Lille Nord De France

LigandPNGBDBM233105(N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N...)
Affinity DataIC50: 2.10E+3nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit�� Lille Nord De France

LigandPNGBDBM233105(N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N...)
Affinity DataIC50: 2.22E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2017
Entry Details Article
PubMed