BDBM23243 1,2(1,5)-Isoxazole, IOA2::4-hydroxy-1,2-oxazole-3-carboxylic acid

SMILES OC(=O)c1nocc1O

InChI Key InChIKey=CGLGFQXJBUOAAP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23243   

TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Bristol

LigandPNGBDBM23243(4-hydroxy-1,2-oxazole-3-carboxylic acid | 1,2(1,5)...)
Affinity DataIC50: 1.60E+4nMpH: 7.5 T: 2°CAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
University of Bristol

LigandPNGBDBM23243(4-hydroxy-1,2-oxazole-3-carboxylic acid | 1,2(1,5)...)
Affinity DataIC50: 1.00E+5nMAssay Description:An LDH enzymatic assay developed for high throughput format was used. The dehydrogenase reaction was run in the lactate to pyruvate direction and cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(malaria parasite P. falciparum)
Treventis

Curated by ChEMBL
LigandPNGBDBM23243(4-hydroxy-1,2-oxazole-3-carboxylic acid | 1,2(1,5)...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum LDHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed