BDBM23228 Oxamic acid derivative, 6::[(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)methyl]carbamoyl}-4-oxo-4H-chromen-7-yl)oxy]ethyl}phenyl)carbamoyl]formic acid

SMILES COc1ccc(CNC(=O)c2cc(=O)c3c(O)cc(OCCc4ccc(NC(=O)C(O)=O)c(c4)C#N)cc3o2)cc1

InChI Key InChIKey=NNFRKDPIXARSJH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 23228   

TargetL-lactate dehydrogenase(Plasmodium falciparum)
University of Mississippi

LigandPNGBDBM23228([(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)me...)
Affinity DataIC50: 8.25E+3nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Bovine)
University of Mississippi

LigandPNGBDBM23228([(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)me...)
Affinity DataIC50: 1.79E+5nMpH: 7.0 T: 2°CAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetL-lactate dehydrogenase(malaria parasite P. falciparum)
University of Mississippi

LigandPNGBDBM23228([(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)me...)
Affinity DataIC50: 8.69E+4nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, mitochondrial(Pig)
University of Mississippi

LigandPNGBDBM23228([(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)me...)
Affinity DataIC50: 5.91E+3nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed
TargetMalate dehydrogenase, cytoplasmic(Pig)
University of Mississippi

LigandPNGBDBM23228([(2-cyano-4-{2-[(5-hydroxy-2-{[(4-methoxyphenyl)me...)
Affinity DataIC50: 1.09E+4nMAssay Description:LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2008
Entry Details Article
PubMed