BDBM23209 (1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydroxy-18-(hydroxymethyl)-1,2,14,18-tetramethyl-8-(prop-1-en-2-yl)pentacyclo[11.8.0.0^{2,10}.0^{5,9}.0^{14,19}]henicosane-5-carboxylic acid::23-Hydroxybetulinic Acid, 25

SMILES [H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](O)[C@@](C)(CO)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C

InChI Key InChIKey=HXWLKAXCQLXHML-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 23209   

TargetGlycogen phosphorylase, muscle form(Rabbit)
China Pharmaceutical University

LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 1.60E+4nMpH: 7.2 T: 2°CAssay Description:The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetGlycogen phosphorylase, muscle form(Rabbit)
China Pharmaceutical University

LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins by microplate reader bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, muscle form(Rabbit)
China Pharmaceutical University

LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetCocaine esterase(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CES2A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 100nMAssay Description:Inhibition of CES1A1 in human liver microsomes using D-luciferin methyl ester as substrate preincubated for 10 mins followed by substrate addition an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
The Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM23209((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CD73 assessed as reduction in inorganic phosphate release upon substrate hydrolysis using AMP/ATP as substrate incubated for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed