BDBM231668 2-(3-(4-Cyanopyridin-2-ylamino)phenoxy)-N-methylacetamide (2b)

SMILES CNC(=O)COc1cccc(Nc2cc(ccn2)C#N)c1

InChI Key InChIKey=HSCBZXMEVJFHPM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 231668   

TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (strain K12))
Astrazeneca R&D Boston

LigandPNGBDBM231668(2-(3-(4-Cyanopyridin-2-ylamino)phenoxy)-N-methylac...)
Affinity DataIC50: 560nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231668(2-(3-(4-Cyanopyridin-2-ylamino)phenoxy)-N-methylac...)
Affinity DataIC50: 4.10E+4nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed