BDBM2312 1,5-Diphenyl-3-methyl-4-ethylpyrazole::1,5-Diphenyl-3-methylpyrazole (DPP) analogue 11::4-ethyl-3-methyl-1,5-diphenyl-1H-pyrazole

SMILES CCc1c(C)nn(c1-c1ccccc1)-c1ccccc1

InChI Key InChIKey=DUMYSQKMPCEFCT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2312   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2312(1,5-Diphenyl-3-methyl-4-ethylpyrazole | 4-ethyl-3-...)
Affinity DataIC50: 1.45E+4nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2312(1,5-Diphenyl-3-methyl-4-ethylpyrazole | 4-ethyl-3-...)
Affinity DataIC50: 520nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2004
Entry Details Article
PubMed