BDBM23076 3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]propan-1-one::alpha-ketooxazole, 11h

SMILES O=C(CCc1ccc(Cc2ccccc2)cc1)c1ncc(o1)-c1ccccn1

InChI Key InChIKey=VAYUMGOSGZBSMF-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23076   

TargetCarboxylic ester hydrolase(Human)
The Scripps Research Institute

LigandPNGBDBM23076(3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Affinity DataIC50: 900nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2008
Entry Details Article
PubMed
TargetDNA ligase 1(Human)
The Scripps Research Institute

LigandPNGBDBM23076(3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Affinity DataKi:  3.20nM ΔG°:  -11.6kcal/mole IC50: 3nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2008
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM23076(3-(4-benzylphenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-...)
Affinity DataKi:  3.20nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed