BDBM229595 US9334288, 9

SMILES C1CCc2c(c3c4c(c(nnn4)N5CCNCC5)sc3nc2N6CCOCC6)C1

InChI Key InChIKey=ZPVQONCMKZBGTB-UHFFFAOYSA-N

Data  3 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 229595   

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataIC50: 1.17nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataEC50:  3.58nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataIC50: 0.984nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataEC50:  3.41nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229595(US9334288, 9)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed