BDBM229594 US9334288, 2

SMILES Cc1ccc2c(c1)C=C(C(=O)N2)CN(CCO)C(=O)Nc3ccccc3F

InChI Key InChIKey=IZEKTGGQNDYMPR-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 229594   

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229594(US9334288, 2)
Affinity DataIC50: 586nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229594(US9334288, 2)
Affinity DataEC50:  233nMAssay Description:PNPG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229594(US9334288, 2)
Affinity DataIC50: 601nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetBeta-glucuronidase(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM229594(US9334288, 2)
Affinity DataEC50:  221nMAssay Description:PheG Assay: Two -glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent