BDBM22913 CHEMBL1237146::CHEMBL498770::Iodophenpropit::{[3-(1H-imidazol-5-yl)propyl]sulfanyl}-N''-[2-(4-iodophenyl)ethyl]methanimidamide

SMILES NC(SCCCc1cnc[nH]1)=NCCc1ccc(I)cc1

InChI Key InChIKey=UBHYDQAARZKHEZ-UHFFFAOYSA-N

Data  46 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 22913   

TargetHrh3 protein(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  0.970nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetHrh3 protein(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.48nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  6nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH3R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2008
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  7.08nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2012
Entry Details
PubMed
TargetHistamine H4 receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in SK-NM-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  7.94nMAssay Description:Displacement of [3H]N-alpha-methylhistamine from human histamine H3 receptor expressed in human SK-N-MC cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Guinea pig)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  13nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  15.8nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in human SK-N-MC cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  170nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetNischarin(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  530nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  530nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetSodium channel protein type 10 subunit alpha(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.71E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  1.98E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  2.28E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  2.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  3.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  4.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi:  8.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetProtachykinin-1(Human)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Chicken)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetGlycine receptor subunit alpha-1(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetGlycine amidinotransferase, mitochondrial(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Vrije Universiteit

Curated by PDSP Ki Database
LigandPNGBDBM22913(CHEMBL1237146 | CHEMBL498770 | {[3-(1H-imidazol-5-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2012
Entry Details Article
PubMed