BDBM22882 2-amino-5(2-aminoethyl)-4-methyl-1,3-selenazole::5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine::Amselamine::CHEMBL60686

SMILES Cc1nc(N)[se]c1CCN

InChI Key InChIKey=PKGAPIBVLGICCE-UHFFFAOYSA-N

Data  3 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22882   

TargetHistamine H2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM22882(5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine | ...)
Affinity DataKd:  9.77E+3nMAssay Description:Affinity to the Histamine H2 receptor was determined expressed in CHO cell using [125I]iodoaminopotentidine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22882(5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine | ...)
Affinity DataKi:  2.51E+3nM ΔG°:  -7.94kcal/molepH: 7.4 T: 2°CAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2008
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Vrije Universiteit Amsterdam

LigandPNGBDBM22882(5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine | ...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]-histamine from human histamine H4 receptor expressed in Sf9 cells coexpressing RGS19, Galphai2, Gbeta1gamma2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM22882(5-(2-aminoethyl)-4-methyl-1,3-selenazol-2-amine | ...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [125I]iodoaminopotentidine from human histamine H2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed