BDBM228784 US9346810, 97

SMILES [O-][N+](=O)c1cc(cnc1NC1CCN(C1)c1ncnc2[nH]ccc12)C#N

InChI Key InChIKey=BYDJCKAAVBGCFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228784   

TargetTyrosine-protein kinase JAK2 [808-1132](Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM228784(US9346810, 97)
Affinity DataIC50: 0.550nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetTyrosine-protein kinase JAK3 [781-1124](Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM228784(US9346810, 97)
Affinity DataIC50: 0.550nMT: 2°CAssay Description:JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent