BDBM228618 BDBM50364365::US9345789, LI-2

SMILES CCOC(=O)\C=C\C(=O)N(CC(N)=O)NC(=O)[C@@H]1CCCN1C(C)=O

InChI Key InChIKey=QXSVKQKIGCAZOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228618   

TargetCathepsin B(Human)
The Leland Stanford Junior University

US Patent
LigandPNGBDBM228618(BDBM50364365 | US9345789, LI-2)
Affinity DataIC50: 1.00E+6nMpH: 5.8Assay Description:Assay buffers consist of 20 mM citric acid, 60 mM disodium hydrogen orthophosphate, 1 mM EDTA, 0.1% CHAPS, 4 mM DTT, pH 5.8 for legumain, 50 mM dihyd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetLegumain(Mouse)
Stanford University School of Medicine

Curated by ChEMBL
LigandPNGBDBM228618(BDBM50364365 | US9345789, LI-2)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of mouse recombinant legumain using Cbz-Ala-Ala-Asn-AMC as substrate measured every 30 secs for 2.5 hrs by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed