BDBM228274 US9555022, Example 02.12

SMILES CCOc1cc(ccc1Nc1nc2ccc(cn2n1)-c1ccc(NC(=O)Cc2ccc(F)cc2)cc1)N1CCOC1=O

InChI Key InChIKey=PGZQARRAOFSUKW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228274   

TargetDual specificity protein kinase TTK(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM228274(US9555022, Example 02.12)
Affinity DataIC50: 1nMpH: 7.7Assay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details
Go to US Patent