BDBM228257 (S)-3-methyl-1-(1-(methanesulfonyl)pyrrolidin-3-yl)-8-(6-phenylpyridin-3-yl)-1H-imidazo[4,5-c][1,5]naphthyridin-2(3H)-one::US10047084, 39

SMILES Cn1c2cnc3ccc(nc3c2n([C@H]2CCN(C2)S(C)(=O)=O)c1=O)-c1ccc(nc1)-c1ccccc1

InChI Key InChIKey=ABPJMGXOUVQILW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228257   

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandPNGBDBM228257(US10047084, 39 | (S)-3-methyl-1-(1-(methanesulfony...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
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