BDBM228256 (S)-3-methyl-8-(6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)-1-(1-(methanesulfonyl)pyrrolidin-3-yl)-1H-imidazol-[4,5-c][1,5]naphthyridin-2(3H)-one::US10047084, 38

SMILES Cn1cc(cn1)-c1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n([C@H]4CCN(C4)S(C)(=O)=O)c3c2n1

InChI Key InChIKey=ISFAMBMLFVNBNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228256   

TargetSerine/threonine-protein kinase mTOR(Human)
Beijing Forelandpharma

US Patent
LigandPNGBDBM228256(US10047084, 38 | (S)-3-methyl-8-(6-(1-methyl-1H-py...)
Affinity DataIC50: 10nMAssay Description:The inhibition of the mTOR protein kinase activity by the compounds was determined by the enzymatic activity assay in vitro. The detection kit suppli...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2018
Entry Details
Go to US Patent